THE MORPHOLOGY AND ACETYLCHOLINE CONTENT OF ISOLATED CEREBRAL CORTICAL SYNAPTIC VESICLES

@article{Whittaker1965THEMA,
  title={THE MORPHOLOGY AND ACETYLCHOLINE CONTENT OF ISOLATED CEREBRAL CORTICAL SYNAPTIC VESICLES},
  author={V. Whittaker and M. Sheridan},
  journal={Journal of Neurochemistry},
  year={1965},
  volume={12}
}
WHEN brain tissue is homogenized under carefully controlled conditions, a high proportion of the presynaptic nerve terminals are torn away from their attachments to form discrete particles for which the term ‘synaptosomes’ has recently been adopted (WHITTAKER, MICHAELSON and KIRKLAND, 1964). These particles may be separated from other subcellular brain particles by differential and density gradient centrifuging. They retain all the structural features of the nerve endings, together with their… Expand
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