THE MORPHOLOGY AND ACETYLCHOLINE CONTENT OF ISOLATED CEREBRAL CORTICAL SYNAPTIC VESICLES

@article{Whittaker1965THEMA,
  title={THE MORPHOLOGY AND ACETYLCHOLINE CONTENT OF ISOLATED CEREBRAL CORTICAL SYNAPTIC VESICLES},
  author={V. Whittaker and M. Sheridan},
  journal={Journal of Neurochemistry},
  year={1965},
  volume={12}
}
WHEN brain tissue is homogenized under carefully controlled conditions, a high proportion of the presynaptic nerve terminals are torn away from their attachments to form discrete particles for which the term ‘synaptosomes’ has recently been adopted (WHITTAKER, MICHAELSON and KIRKLAND, 1964). These particles may be separated from other subcellular brain particles by differential and density gradient centrifuging. They retain all the structural features of the nerve endings, together with their… Expand
View on Wiley
ncbi.nlm.nih.gov
206 Citations
Background Citations
12
Methods Citations
3

Topics from this paper

      206 Citations

      Citation Type

      Citation Type

      SOME PROPERTIES OF SYNAPTIC MEMBRANES ISOLATED FROM THE CENTRAL NERVOUS SYSTEM *
      • V. Whittaker
      • Chemistry, Medicine
      • Annals of the New York Academy of Sciences
      • 1966
      • 128
      The preparation and characterization of synaptic vesicles of high purity
      • 184
      The morphology of the contact region of vertebrate synaptosomes
      • D. G. Jones
      • Biology, Medicine
      • Zeitschrift für Zellforschung und Mikroskopische Anatomie
      • 2004
      • 15
      Thirty years of synaptosome research
      • 149
      The Synaptic Vesicle
      • 153
      THE SYNTHESIS AND STORAGE OF ACETYLCHOLINE IN THE STRIATUM *
      • A. Sattin
      • Chemistry, Medicine
      • Journal of neurochemistry
      • 1966
      • 41
      Tissue fractionation methods in brain research.
      • 7
      The subcellular fractionation of the electric organ of Torpedo
      • 28
      BIOCHEMICAL ORGANIZATION OF CHOLINERGIC NERVE TERMINALS IN THE CEREBRAL CORTEX
      • 21
      Isolation and Study of Synaptic Vesicles
      • 10
      ...
      1
      2
      3
      4
      5
      ...

      References

      SHOWING 1-10 OF 22 REFERENCES
      ISOLATION OF SYNAPTIC VESICLES AND STRUCTURAL ORGANIZATION OF THE ACETYLCHOLINE SYSTEM WITHIN BRAIN NERVE ENDINGS *
      • 384
      Distribution of lipids in subcellular particles of guinea-pig brain.
      • 417
      • PDF
      Investigations on the Storage Sites of Biogenic Amines in the Central Nervous System
      • 36
      Intracellular distributions of acetylcholine and choline acetylase
      • 246
      Acetylcholine‐sensitive cells in the cerebral cortex
      • 403
      The spontaneous release of acetylcholine from the denervated hemidiaphragm of the rat
      • 169
      NEGATIVE STAINING OF PHOSPHOLIPIDS AND THEIR STRUCTURAL MODIFICATION BY SURFACE-ACTIVE AGENTS AS OBSERVED IN THE ELECTRON MICROSCOPE.
      • 1,270
      Permanganate—A New Fixative for Electron Microscopy
      • J. Luft
      • Biology, Medicine
      • The Journal of biophysical and biochemical cytology
      • 1956
      • 581
      • PDF
      A MODIFIED PROCEDURE FOR LEAD STAINING OF THIN SECTIONS
      • G. Millonig
      • Biology, Medicine
      • The Journal of biophysical and biochemical cytology
      • 1961
      • 1,282
      • PDF
      Electron microscopic particle counts on herpes virus using the phosphotungstate negative staining technique.
      • 117
      ...
      1
      2
      3
      ...