THE IONIC BASIS OF ELECTRICAL ACTIVITY IN NERVE AND MUSCLE

@article{Hodgkin1951THEIB,
  title={THE IONIC BASIS OF ELECTRICAL ACTIVITY IN NERVE AND MUSCLE},
  author={Alan Lloyd Hodgkin},
  journal={Biological Reviews},
  year={1951},
  volume={26}
}
  • A. Hodgkin
  • Published 1 November 1951
  • Biology
  • Biological Reviews
1 Four methods of determining the potential difference across the surface membrane of living cells are described. 2 In a wide range of excitable tissues the resting membrane potential is of the order of 50–100 mV. and the action potential of the order of 80–130 mV. 3 At the height of activity the potential difference across the membrane is reversed by 30–50 mV. 4 The potassium concentration inside most excitable cells is 20–50 times greater than that in the external medium; sodium is 3–15 times… 

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