THE HOST RESPONSE TO CALMETTE-GUÉRIN BACILLUS INFECTION IN MICE

@article{Blanden1969THEHR,
  title={THE HOST RESPONSE TO CALMETTE-GU{\'E}RIN BACILLUS INFECTION IN MICE},
  author={R. Blanden and M. J. Lefford and G. Mackaness},
  journal={The Journal of Experimental Medicine},
  year={1969},
  volume={129},
  pages={1079 - 1107}
}
Heterologous organisms (L. monocytogenes and S. typhimurium) were used to study the rate of development, magnitude, and persistence of the antimicrobial resistance engendered in mice by vaccination with BCG. These same methods were used to investigate the influence of prior vaccination on the host response to reinfection. The rate of onset and magnitude of the resistance produced by BCG varied with the vaccinating dose. Increased resistance was detected within 48 hr of injecting large numbers… Expand
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