THE EFFECT OF CYTOCHALASIN J ON KINETOCHORE STRUCTURE IN PTK1CELLS IS MITOTIC CYCLE DEPENDENT

@article{Wrench2001THEEO,
  title={THE EFFECT OF CYTOCHALASIN J ON KINETOCHORE STRUCTURE IN PTK1CELLS IS MITOTIC CYCLE DEPENDENT},
  author={G. Wrench and J. Snyder},
  journal={Cell Biology International},
  year={2001},
  volume={25}
}
  • G. Wrench, J. Snyder
  • Published 2001
  • Chemistry, Medicine
  • Cell Biology International
  • Mitotic PtK1cells were arrested in mitosis with nocodazole to determine the effect of cytochalasin J (CJ) on kinetochore structure in arrested and nocodazole‐released cells. In previous studies it was shown that CJ had a more pronounced effect on alteration of kinetochore structure and spindle microtubule (MT) architecture when applied during prophase or prometaphase. In this study, mitotic cells were treated at preanaphase for 10min with 1μg/ml nocodazole, or in 1μg/ml nocodazole and 10μg/ml… CONTINUE READING
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