THE DISTRIBUTION OF COLONY-FORMING CELLS AMONG SPLEEN COLONIES.

@article{Siminovitch1963THEDO,
  title={THE DISTRIBUTION OF COLONY-FORMING CELLS AMONG SPLEEN COLONIES.},
  author={L. Siminovitch and E. McCulloch and J. Till},
  journal={Journal of cellular and comparative physiology},
  year={1963},
  volume={62},
  pages={
          327-36
        }
}
Progenitor cells that are recognized by their ability to form colonies of descendants in the spleens of irradiated mice have the capacity for self-renewal. The distribution of new colony-forming cells per colony is extremely heterogeneous, indicating lax control of self-renewal. The capacities of colony-forming cells for self-renewal, for extensive proliferation, and for giving rise to differentiated descendants, fulfill three requirements for studies of stem cells. Thus, colony-forming cells… Expand
Physical separation of hemopoietic stem cells from cells forming colonies in culture
PHYSICAL SEPARATION OF HEMOPOIETIC STEM CELLS DIFFERING IN THEIR CAPACITY FOR SELF-RENEWAL
The cloning of normal "mast" cells in tissue culture.
The self renewal probability of hemopoietic stem cells
...
1
2
3
4
5
...

References

SHOWING 1-9 OF 9 REFERENCES
Les clones de cellules hematopoietiques in vivo
  • Rev . Franc Etudes Clin . et Biol .
  • 1963
A method for investigation of stem-cell kinetics.
Anatomic and physiologic facts and hypotheses about hemopoietic proliferating systems
  • The Kinetics of Cellular Proliferation
  • 1959