THE CLINICAL AND RADIOLOGICAL INVESTIGATION OF TWO CASES WITH NEUROTOXICITY FOLOWING METHOTREXATE TREATMENT
@inproceedings{Mine2008THECA, title={THE CLINICAL AND RADIOLOGICAL INVESTIGATION OF TWO CASES WITH NEUROTOXICITY FOLOWING METHOTREXATE TREATMENT}, author={Mine and Mevl{\"u}t and A. Polat}, year={2008} }
Methotrexate is a chemotherapeutic agent which is a member of antimetabolite group drugs, and used in neoplastic diseases such as acute lymphoblastic leukemia, lymphoma and osteosarcoma. Methotrexate has various side effects such as myelosuppression, mucositis, hepatic and tubular necrosis, central nervous system toxicities. In this article, clinical and radiological findings and longterm follow-up of two cases with central nervous system neurotoxicity following methotrexate treatment are… CONTINUE READING
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