THE ASSAY OF OXYTOCIN IN THE PRESENCE OF VASOPRESSIN ON THE DIOESTRUS UTERUS OF THE RAT
@article{Lockett1957THEAO, title={THE ASSAY OF OXYTOCIN IN THE PRESENCE OF VASOPRESSIN ON THE DIOESTRUS UTERUS OF THE RAT}, author={Mary F. Lockett and Gwilym Ellis Lane Owen}, journal={Journal of Pharmacy and Pharmacology}, year={1957}, volume={9} }
EXTRACTS of whole posterior pituitary lobes of cattle are known to contain oxytocin and vasopressin in nearly equal proportions. Since oxytocin is assayed in these extracts, the circumstances under which, and the extent to which, vasopressin may interfere with these estimates should be known. Oxytocin is now assayed either by its depressor action on the fowl's blood pressure1 or by the graded contractions which it induces in the rat's dioestrus uterus2. Whereas the possible interference by…
3 Citations
Studies on the mode of action of vasopressin on the isolated proximal colon of the guinea‐pig
- Biology, MedicineBritish journal of pharmacology
- 1969
It is concluded that the action of vasopressin on proximal colon is unlike its action on other smooth muscle and is mediated by nervous tissue.
Mode of action of vasopressin on isolated proximal colon of the guinea-pig.
- Biology, MedicineBritish journal of pharmacology and chemotherapy
- 1966
Experiments are described which provide evidence in support of the suggestion that vasopressin might be capable of effecting a contraction of this tissue by stimulating nervous elements associated with the smooth muscle.
References
An Examination Of Factors Affecting The Precision Of The Assay Of The Oxytocic Hormone In Posterior Pituitary Lobe Preparations
- Biology, MedicineThe Journal of pharmacy and pharmacology
- 1949
Work has been described which shows the errors which may be encountered under different experimental conditions of the uterine assay of oxytocin, or commercial posterior pituitary extracts where the…