Corpus ID: 73993297

THE ADOPTIVE TRANSFER OF CARTILAGE PROTEOGLYCAN (AGGRECAN)-INDUCED ARTHRITIS TO SCID MICE REQUIRES CO-ADMINISTRATION OF T CELLS AND ANTIGEN

@inproceedings{Pkwy2001THEAT,
  title={THE ADOPTIVE TRANSFER OF CARTILAGE PROTEOGLYCAN (AGGRECAN)-INDUCED ARTHRITIS TO SCID MICE REQUIRES CO-ADMINISTRATION OF T CELLS AND ANTIGEN},
  author={W. Pkwy},
  year={2001}
}
8cells) or Lympholyte-purified spleen lymphocytes (2x10 7 cells, both T and B cells) injected together with PG (100�g intraperitoneally). SCID mice injected with splenocytes exhibited earlier arthritis (24±6.4 days after the injection) with lower severity (3.9±1.8 cumulative arthritis score), than those injected with purified lymphocytes (30±10.3 days onset and 7.7±1.9 severity score) (Fig.1). All these celltransfers from arthritic BALB/c mice into SCID mice resulted in 100% incidence, and the… Expand