• Biology
  • Published 2006

THALASSEMIC MUTATIONS IN SOUTHERN IRAN

@inproceedings{Rahimi2006THALASSEMICMI,
  title={THALASSEMIC MUTATIONS IN SOUTHERN IRAN},
  author={Zohreh Rahimi and A Veysi Raigani and Ahmad Merat and Mandana Haghshenas and Nathalie G{\'e}rard and Ronald L. Nagel and Rajagopal Krishnamoorthy},
  year={2006}
}
Background: Approximately 180 mutations have been described in β-thalassemia worldwide with specific spectrum in each ethnic population. This study determines the spectrum and the frequency of β-thalassemia mutations in patients with β-thalassemia trait and sickle cell-β-thalassemia. Methods: Fifteen compound heterozygous sickle cell thalassemia (SCT) and 23 β-thalassemia trait patients were studied using reverse dot blot, denaturing gradient gel electrophoresis and direct genomic sequencing… CONTINUE READING

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