TH17 cells are increased in the peripheral blood of patients with SAPHO syndrome.

@article{Firinu2014TH17CA,
  title={TH17 cells are increased in the peripheral blood of patients with SAPHO syndrome.},
  author={Davide Firinu and Maria Pina Barca and Maria Maddalena Lorrai and Silvia Perra and Stefano Cabras and Emma Muggianu and Maria Luisa Di Martino and Paolo Emilio Manconi and Stefano R Del Giacco},
  journal={Autoimmunity},
  year={2014},
  volume={47 6},
  pages={389-94}
}
To assess whether the immune derangement previously observed in SAPHO syndrome could be linked to variations in blood TH1, TH2 or TH17 lymphocytes frequency. Seven SAPHO patients with a protracted course of the disease were studied ex-vivo for intracellular cytokines production by means of flow-cytometry and compared with matched groups of Psoriatic Arthritis patients and healthy controls. The Kruskal-Wallis test on the median of the three categories showed that there is a significant… CONTINUE READING
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