TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation.

@article{Olsen2011TH1AT,
  title={TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation.},
  author={Trine Olsen and Renathe Rismo and Guanglin Cui and Rasmus Goll and Ingrid Christiansen and Jon Florholmen},
  journal={Cytokine},
  year={2011},
  volume={56 3},
  pages={633-40}
}
BACKGROUND Crohn's disease (CD) and ulcerative colitis (UC) have been associated with a T helper1 (TH1) and a TH2 cytokine profile, respectively. Recently, a TH17 lineage has been introduced, but their role in the inflammation of CD and UC is not fully understood. AIM To characterize the cytokines directing the TH17 cells and their interactions with TH1 cells in the mucosa of untreated patients with CD and UC. METHOD Seventy-nine patients with untreated UC, 32 patients with untreated CD and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Similar Papers

Loading similar papers…