TH1-TH2 response and the atopy risk in patients with reproduction failure.

  title={TH1-TH2 response and the atopy risk in patients with reproduction failure.},
  author={Jana Hanzl{\'i}kov{\'a} and Zdenka Ulcov{\'a}-Gallov{\'a} and Ivana Malkusov{\'a} and Frantisek Sefrna and Petr Panzner},
  journal={American journal of reproductive immunology},
  volume={61 3},
PROBLEM Enhanced TH2 activity is characteristic for atopic diseases and is observed also in physiological pregnancy. The immune causes of repeated pregnancy losses and/or repeated in vitro fertilization failure may be associated with TH2 hypoactivity. The association with frequency of atopic diseases is unclear. METHOD OF STUDY Intracellular production of IL-4 and IFN-gamma by peripheral CD4+ T lymphocytes was studied, as well as serum levels of total and allergen specific IgE. Simultaneously… CONTINUE READING
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