TGFBR1*6A and cancer risk: a meta-analysis of seven case-control studies.

@article{Kaklamani2003TGFBR16AAC,
  title={TGFBR1*6A and cancer risk: a meta-analysis of seven case-control studies.},
  author={Virginia G. Kaklamani and Nanjiang Hou and Yiansong Bian and Jennifer A. Reich and Kenneth Offit and Loren Scott Michel and Wendy S. Rubinstein and A. Douglas Rademaker and Boris C. Pasche},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2003},
  volume={21 17},
  pages={
          3236-43
        }
}
PURPOSE TGFBR1*6A is a hypomorphic polymorphic allele of the type I transforming growth factor beta receptor (TGFBR1). TGFBR1*6A is a candidate tumor susceptibility allele that has been associated with an increased incidence of various types of cancer. This study was undertaken to analyze all published case-control studies on TGFBR1*6A and cancer and determine whether TGFBR1*6A is associated with cancer. PATIENTS AND METHODS All published case-control studies assessing the germline frequency… CONTINUE READING
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