TGFB1 gene polymorphisms: their relevance in the susceptibility to Helicobacter pylori-related diseases

@article{GarcaGonzlez2006TGFB1GP,
  title={TGFB1 gene polymorphisms: their relevance in the susceptibility to Helicobacter pylori-related diseases},
  author={Mara Asuncin Garc{\'i}a-Gonz{\'a}lez and Mark H.P. Strunk and Elena Piazuelo and Rafael Benito and Santos Santolaria and Pilar Jim{\'e}nez and Federico Sope{\~n}a and Cristina Pascual and Miguel Angel Sim{\'o}n and Ricardo S{\'a}inz and A. Iriarte Lanas},
  journal={Genes and Immunity},
  year={2006},
  volume={7},
  pages={640-646}
}
Recent studies have revealed elevated expression of transforming growth factor β1 (TGF-β1) in gastric mucosa of patients with gastric cancer (GC) and those undergoing ulcer repair. As production of TGF-β1 is genetically regulated, we aimed to assess whether functional polymorphisms of the TGFB1 gene are involved in susceptibility to and clinical… CONTINUE READING