TGF beta1 and TGF beta2 and their role in posthemorrhagic hydrocephalus following SAH and IVH.

@article{Kaestner2013TGFBA,
  title={TGF beta1 and TGF beta2 and their role in posthemorrhagic hydrocephalus following SAH and IVH.},
  author={Stefanie Kaestner and Ioannis Dimitriou},
  journal={Journal of neurological surgery. Part A, Central European neurosurgery},
  year={2013},
  volume={74 5},
  pages={
          279-84
        }
}
OBJECTIVE Posthemorrhagic hydrocephalus (pHC) is a serious complication following subarachnoid hemorrhage (SAH) and intraventricular hemorrhage (IVH). Besides known clinical predictors, different cytokines have drawn attention to the development of chronic hydrocephalus. Transforming growth factor (TGF) β1 and TGF β2 are involved in fibrogenesis, scar formation, cell survival, and tissue differentiation and may play a role in the occurrence of pHC. TGF β1 is stored in platelets in large amount… CONTINUE READING
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