TGF-beta signaling is required for multiple processes during Xenopus tail regeneration.

@article{Ho2008TGFbetaSI,
  title={TGF-beta signaling is required for multiple processes during Xenopus tail regeneration.},
  author={Diana M. Ho and Malcolm R Whitman},
  journal={Developmental biology},
  year={2008},
  volume={315 1},
  pages={203-16}
}
Xenopus tadpoles can fully regenerate all major tissue types following tail amputation. TGF-beta signaling plays essential roles in growth, repair, specification, and differentiation of tissues throughout development and adulthood. We examined the localization of key components of the TGF-beta signaling pathway during regeneration and characterized the effects of loss of TGF-beta signaling on multiple regenerative events. Phosphorylated Smad2 (p-Smad2) is initially restricted to the p63+ basal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Similar Papers

Loading similar papers…