TGF-beta in renal injury and disease.

  title={TGF-beta in renal injury and disease.},
  author={Erwin P. B{\"o}ttinger},
  journal={Seminars in nephrology},
  volume={27 3},
Chronic progressive kidney diseases typically are characterized by loss of differentiated epithelial cells and activation of mesenchymal cell populations leading to renal fibrosis in response to a broad range of diverse renal injuries. Recent evidence has indicated that epithelial microinjury leads to unbalanced epithelial-mesenchymal communication to… CONTINUE READING