Corpus ID: 496701

TGF-beta and the regulation of neuron survival and death.

  title={TGF-beta and the regulation of neuron survival and death.},
  author={K. Krieglstein and J. Strelau and A. Schober and A. Sullivan and K. Unsicker},
  journal={Journal of physiology, Paris},
  volume={96 1-2},
  • K. Krieglstein, J. Strelau, +2 authors K. Unsicker
  • Published 2002
  • Medicine
  • Journal of physiology, Paris
  • Transforming growth factor-betas (TGF-betas) constitute a superfamily of multifunctional cytokines with important implications in morphogenesis, cell differentiation, and tissue remodeling. In the developing nervous system, TGF-beta2 and -beta3 occur in radial and astroglial cells as well as in many populations of postmitotic, differentiating neurons. TGF-beta1 is restricted to the choroid plexus and meninges. In addition to functions related to glial cell maturation and performances, TGF-beta2… CONTINUE READING
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