TGF-beta and the evolution of nematode parasitism.

  title={TGF-beta and the evolution of nematode parasitism.},
  author={Mark E Viney and Fiona J Thompson and Matt Crook},
  journal={International journal for parasitology},
  volume={35 14},
The many similarities between arrested dauer larvae of free-living nematodes and infective L3 of parasitic nematodes has led to suggestions that they are analogous lifecycle stages. The control of the formation of dauer larvae in Caenorhabditis elegans is well understood, with a TGF-beta-superfamily growth factor playing a central role. Recent analyses of the expression of homologous TGF-beta genes in parasitic nematodes has allowed this analogy to be tested; but the results so far do not… CONTINUE READING

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