TGF-beta and IL-17 serum levels and specific immunotherapy.

  title={TGF-beta and IL-17 serum levels and specific immunotherapy.},
  author={Giorgio Ciprandi and Mara De Amici and Simone Negrini and Gianluigi L. Marseglia and Maria Angela Tosca},
  journal={International immunopharmacology},
  volume={9 10},
Two new T cell subsets may be involved in allergic rhinitis (AR) pathogenesis: Th17 and T regulatory cells, mainly producing IL-17 and TGF-beta respectively. Successful Sublingual Immunotherapy (SLIT) induces relevant immunological changes, thus the aim of this study was to evaluate serum IL-17 and TGF-beta levels in AR patients treated with SLIT for 2 years. Patients' blood samples were collected before initiating SLIT (baseline), three months after the end of the first pre-seasonal SLIT… CONTINUE READING

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