TGF-β1 mediates 70-kDa heat shock protein induction due to ultraviolet irradiation in human skin fibroblasts

@article{Cao1999TGF1M7,
  title={TGF-$\beta$1 mediates 70-kDa heat shock protein induction due to ultraviolet irradiation in human skin fibroblasts},
  author={Y. Cao and N. Ohwatari and Takaaki Matsumoto and M. Kosaka and A. Ohtsuru and S. Yamashita},
  journal={Pfl{\"u}gers Archiv},
  year={1999},
  volume={438},
  pages={239-244}
}
Abstract Ultraviolet B (UVB) alters the expression of heat shock protein 70 (HSP70) in cultured fibroblast cells derived from human skin. However, the nature of the signal transduction pathway remains to be determined. Transforming growth factor-β (TGF-β) has a large variety of biological functions, including cell growth control, modulation of inflammation and immunoregulation. In this study, we examined whether TGF-β is associated with the process of HSP70 expression induced by UVB irradiation… Expand

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