TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation

@inproceedings{Chen2012TGFAB,
  title={TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation},
  author={Guiqian Chen and Chuxia Deng and Yi-Ping Li},
  booktitle={International journal of biological sciences},
  year={2012}
}
Transforming growth factor-beta (TGF-β)/bone morphogenic protein (BMP) signaling is involved in a vast majority of cellular processes and is fundamentally important throughout life. TGF-β/BMPs have widely recognized roles in bone formation during mammalian development and exhibit versatile regulatory functions in the body. Signaling transduction by TGF-β/BMPs is specifically through both canonical Smad-dependent pathways (TGF-β/BMP ligands, receptors and Smads) and non-canonical Smad… CONTINUE READING

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References

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SHOWING 1-10 OF 172 REFERENCES

Conditional deletion of BMP7 from the limb skeleton does not affect bone formation or fracture repair.

  • Journal of orthopaedic research : official publication of the Orthopaedic Research Society
  • 2009
VIEW 12 EXCERPTS
HIGHLY INFLUENTIAL

Stimulation of osteoblastic cell differentiation by Notch.

  • Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 2002
VIEW 11 EXCERPTS
HIGHLY INFLUENTIAL

Akt phosphorylates and regulates the osteogenic activity of Osterix.

  • Biochemical and biophysical research communications
  • 2011
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL