TGFα Transgenic Mice

@article{Greten2001TGFTM,
  title={TGF$\alpha$ Transgenic Mice},
  author={Florian R. Greten and Martin Wagner and Christoph K. Weber and Ulrich Zechner and Guido Adler and Roland M. Schmid},
  journal={Pancreatology},
  year={2001},
  volume={1},
  pages={363 - 368}
}
Pancreatic cancer is a devastating disease with a fatal prognosis due to late diagnosis and resistance to radiation and chemotherapy. The average survival after diagnosis is still 3 to 8 months. In the last few years genetic alterations in cancer-causing genes have been identified in tumors and putative premalignant lesions using microdissection techniques. However, the functional consequence of these genetic alterations for pancreatic growth and differentiation is unknown. TGFα overexpressed… 
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