TFT and 6TG resistance of mouse lymphoma cells to analogs of azacytidine.

Abstract

5-Azacytidine (5-aza-CR) and six of its analogs were examined for their ability to induce trifluorothymidine (TFT) and/or 6-thioguanine (6TG) resistance in L5178Y mouse lymphoma cells. These analogs were 5-aza-2'-deoxycytidine (5-aza-CdR), 5-fluoro-2'-deoxycytidine (5-FCdR), 5,6-dihydro-5-azacytidine (dH-aza-CR), 6-azacytidine (6-aza-CR), cytidine (CR) and… (More)

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Cite this paper

@article{McGregor1989TFTA6, title={TFT and 6TG resistance of mouse lymphoma cells to analogs of azacytidine.}, author={Douglas B. McGregor and Alison G. M. Brown and P J Cattanach and Wendy Shepherd and Colin Riach and D S Daston and William J. Caspary}, journal={Carcinogenesis}, year={1989}, volume={10 11}, pages={2003-8} }