TFPI-2 methylation predicts poor prognosis in non-small cell lung cancer.

@article{Wu2012TFPI2MP,
  title={TFPI-2 methylation predicts poor prognosis in non-small cell lung cancer.},
  author={Duoguang Wu and Lihua Xiong and Shuoming Wu and Ming Jiang and Guiyong Lian and Minghui Wang},
  journal={Lung cancer},
  year={2012},
  volume={76 1},
  pages={106-11}
}
BACKGROUND Methylation of human tissue factor pathway inhibitor-2 (TFPI-2) gene has been detected in several types of cancer, including non-small cell lung cancer (NSCLC). However, an association between the methylation status of TFPI-2 gene and prognosis has not yet been investigated. METHODS Methylation of TFPI-2 gene was examined in a consecutive series of 133 non-metastatic NSCLC patients using methylation-specific PCR (MSP). Univariate and multivariate analyses were conducted to… CONTINUE READING
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