TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription.

@article{Zhou2001TFIIHIC,
  title={TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription.},
  author={Meisheng Zhou and Sergei Nekhai and Diana C Bharucha and Ajit Kumar and Hongfei Ge and David H Price and Jean Marc Egly and John N. Brady},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 48},
  pages={44633-40}
}
Tat stimulates human immunodeficiency virus, type 1 (HIV-1), transcription elongation by recruitment of the human transcription elongation factor P-TEFb, consisting of CDK9 and cyclin T1, to the TAR RNA structure. It has been demonstrated further that CDK9 phosphorylation is required for high affinity binding of Tat/P-TEFb to the TAR RNA structure and that… CONTINUE READING