TERT promoter mutation is uncommon in acral lentiginous melanoma.

@article{Liau2014TERTPM,
  title={TERT promoter mutation is uncommon in acral lentiginous melanoma.},
  author={Jau-Yu Liau and J H Tsai and Yung-Ming Jeng and Chia-Yu Chu and Kuan-Ting Kuo and Cher-wei Liang},
  journal={Journal of cutaneous pathology},
  year={2014},
  volume={41 6},
  pages={504-8}
}
BACKGROUND Melanoma is a heterogeneous group of diseases with distinct sets of genetic changes. Recurrent and mutually exclusive C>T or CC>TT transition mutations were identified in the promoter region of the reverse transcriptase catalytic subunit of the telomerase gene (TERT) in melanoma recently, and it was suggested that they enhanced the expression of… CONTINUE READING