TERT Polymorphism rs2853669 Influences on Lung Cancer Risk in the Korean Population

@inproceedings{Yoo2015TERTPR,
  title={TERT Polymorphism rs2853669 Influences on Lung Cancer Risk in the Korean Population},
  author={Seung Soo Yoo and Sook Kyung Do and Jin Eun Choi and Shin Yup Lee and Jaehee Lee and Seung Ick Cha and Chang Ho Kim and Jae Yong Park},
  booktitle={Journal of Korean medical science},
  year={2015}
}
Short telomeres are known as one of the risk factors for human cancers. The present study was conducted to evaluate the association between 6 polymorphisms, which were related with short telomere length in the Korean population, and lung cancer risk using 1,100 cases and 1,096 controls. Among the 6 polymorphisms, TERT rs2853669 was significantly associated with increased lung cancer risk under a recessive model (odds ratio [OR]=1.38, 95% confidence interval [CI]=1.05-1.81, P=0.02). The effect… CONTINUE READING