TERS detection of αVβ3 integrins in intact cell membranes.


Integrins are important membrane receptors that form focal adhesions with the extracellular matrix and are transmembrane signaling proteins. We demonstrate that nanoparticles functionalized with c-RGDfC ligands bind to intact cell membranes and selectively enhance the amino acid signals of the integrin receptor when coupled with tip-enhanced Raman… (More)
DOI: 10.1002/cphc.201402466


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