TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI).


Tumor endothelial marker (TEM)8 was uncovered as a gene expressed predominantly in tumor endothelium, and its protein product was recently identified as the receptor for anthrax toxin. Here, we demonstrate that TEM8 protein is preferentially expressed in endothelial cells of neoplastic tissue. We used the extracellular domain of TEM8 to search for ligands… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.