TEGDMA and filler particles from dental composites additively attenuate LPS-induced cytokine release from the macrophage cell line RAW 264.7

@article{Mathisen2014TEGDMAAF,
  title={TEGDMA and filler particles from dental composites additively attenuate LPS-induced cytokine release from the macrophage cell line RAW 264.7},
  author={Gro Haarklou Mathisen and Vibeke E Ansteinsson and Jan Tore Samuelsen and Rune Becher and Jon E Dahl and Anette Kocbach B\olling},
  journal={Clinical Oral Investigations},
  year={2014},
  volume={19},
  pages={61-69}
}
Due to incomplete curing and material degradation, cells in the oral cavity may be exposed to monomers and filler particles from dental composite fillings. The objective of the present study was to investigate if combined exposures to particles and a methacrylate monomer from composite fillings resulted in additive effects on the macrophage immune response. Two filler particles, Nanosilica (12 nm) and Quartz (1 μm), were studied at concentrations 0.5–4 μg/cm2, while the methacrylate monomer… CONTINUE READING

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