TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma.

@article{Kannan2012TECAM,
  title={TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma.},
  author={Yashaswini Kannan and Mark S Wilson},
  journal={Journal of clinical & cellular immunology},
  year={2012},
  volume={Suppl 12},
  pages={
          11
        }
}
Significant advances in our understanding of the signalling events during T cell development and differentiation have been made in the past few decades. It is clear that ligation of the T cell receptor (TCR) triggers a series of proximal signalling cascades regulated by an array of protein kinases. These orchestrated and highly regulated series of events, with differential requirements of particular kinases, highlight the disparities between αβ+CD4+ T cells. Throughout this review we summarise… CONTINUE READING

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