TDP-43 in the Population: Prevalence and Associations with Dementia and Age.

@article{Keage2014TDP43IT,
  title={TDP-43 in the Population: Prevalence and Associations with Dementia and Age.},
  author={Hannah A. D. Keage and Sally Hunter and Fiona E. Matthews and Paul G. Ince and John R. Hodges and Suvi R K Hokkanen and J. Robin Highley and Tom Dening and Carol Brayne},
  journal={Journal of Alzheimer's disease : JAD},
  year={2014}
}
Background: The significance of TDP-43 pathology in relation to aging and dementia in the population is unclear. Objective: We aimed to determine the prevalence of transactive response DNA-binding protein of 43 kDA (TDP-43) neuronal inclusions in a population-based sample, and associations with age group at death (≤90 and >90 years) and clinical dementia… CONTINUE READING