TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies

Abstract

Frontotemporal lobar degeneration (FTLD) is one of the leading causes of dementia after Alzheimer's disease. A high-ranking candidate to become a diagnostic marker for a major pathological subtype of FTLD is the transactive response DNA binding protein of 43 kDa (TDP-43). The main objective is to elucidate which antibodies are specific for pathological TDP… (More)
DOI: 10.1186/s40478-015-0195-1

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Cite this paper

@inproceedings{Goossens2015TDP43AA, title={TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies}, author={Joery Goossens and Eugeen Vanmechelen and John Q. Trojanowski and Virginia M-Y Lee and Christine Van Broeckhoven and Julie van der Zee and Sebastiaan Engelborghs}, booktitle={Acta neuropathologica communications}, year={2015} }