TCR3: a third T-cell receptor in the chicken.

  title={TCR3: a third T-cell receptor in the chicken.},
  author={C H Chen and J T Sowder and Jill M. Lahti and Josef Cihak and Uli L{\"o}sch and Max D. Cooper},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={86 7},
Avian homologues of mammalian gamma delta and alpha beta T-cell antigen receptors, TCR1 and TCR2, have been identified with monoclonal antibodies. These TCR isotypes are associated with the avian CD3 proteins on the T-cell surface. During chick development, T-cell subpopulations bearing CD3/TCR1 or CD3/TCR2 receptor complexes are generated sequentially in the thymus and seeded to the periphery in the same order. In this study, we used two-color immunofluorescence to identify the subsequent… CONTINUE READING

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