TCR gamma delta bearing T lymphocytes infiltrating human primary cutaneous melanomas.

@article{Bachelez1992TCRGD,
  title={TCR gamma delta bearing T lymphocytes infiltrating human primary cutaneous melanomas.},
  author={H Bachelez and B{\'e}atrice Flageul and Laurent Degos and Laurence Boumsell and Armand Bensussan},
  journal={The Journal of investigative dermatology},
  year={1992},
  volume={98 3},
  pages={369-74}
}
In situ immunophenotypic studies show that tumor infiltrating T lymphocytes from six of 11 fresh cutaneous primary melanomas tested contain T-cell receptor gamma delta expressing cells whereas those from 8 metastatic melanomas did not. In three cases these cells represent an unexpectedly high proportion of the lymphocytic infiltrate, ranging from 15 to 25%. This elevated percentage is maintained when tumor infiltrating lymphocytes are propagated in vitro for 2 or 3 weeks in the presence of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…