TBD/Al2O3: a novel catalytic system for dynamic intermolecular aldol reactions that exhibit complex system behaviour.

@article{MartnezCastaeda2012TBDAl2O3AN,
  title={TBD/Al2O3: a novel catalytic system for dynamic intermolecular aldol reactions that exhibit complex system behaviour.},
  author={{\'A}ngel Mart{\'i}nez-Casta{\~n}eda and Humberto Rodr{\'i}guez-Solla and Carmen Concell{\'o}n and Vicente del Amo},
  journal={Organic & biomolecular chemistry},
  year={2012},
  volume={10 10},
  pages={1976-81}
}
The heterogeneous system TBD/Al(2)O(3) is an efficient catalyst for the intermolecular aldol reaction between ketones and aromatic aldehydes. This system operates with low catalysts loading (10%), in water or organic solvents, and with short reaction times. The desired aldol products are rendered cleanly. Experiments confirmed that this aldol protocol is… CONTINUE READING