TBC domain family, member 15 is a novel mammalian Rab GTPase-activating protein with substrate preference for Rab7.

@article{Zhang2005TBCDF,
  title={TBC domain family, member 15 is a novel mammalian Rab GTPase-activating protein with substrate preference for Rab7.},
  author={Xiang-Ming Zhang and Bong J. Walsh and Christina A Mitchell and Tony Rowe},
  journal={Biochemical and biophysical research communications},
  year={2005},
  volume={335 1},
  pages={154-61}
}
Ypt/Rabs are Ras-related GTPases that function as key regulators of intracellular vesicular trafficking. Their slow intrinsic rates of GTP hydrolysis are catalyzed by GTPase-activating proteins (GAPs). Ypt/Rab-GAPs constitute a family of proteins that contain a TBC (Tre-2/Bub2/Cdc16) domain. Only three of the 51 family members predicted in the human genome are confirmed Ypt/Rab-GAPs. Here, we report the identification and characterization of a novel mammalian Ypt/Rab-GAP, TBC domain family… CONTINUE READING
24 Citations
43 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Rab GTPases

  • Pereira-Leal
  • Methods in Molecular Biology
  • 2015

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Hammer III , Identification of an organelle receptor for myosinVa

  • F. Jollivet A. Echard, O. Martinez, J. J. Lacapere, A. Rousselet, I. Janoueix-Lerosey, B. Goud
  • Nat . Cell Biol .
  • 2002

Similar Papers

Loading similar papers…