TAZ: a beta-catenin-like molecule that regulates mesenchymal stem cell differentiation.

@article{Hong2006TAZAB,
  title={TAZ: a beta-catenin-like molecule that regulates mesenchymal stem cell differentiation.},
  author={Jeong-Ho Hong and Michael B. Yaffe},
  journal={Cell cycle},
  year={2006},
  volume={5 2},
  pages={176-9}
}
Regulating the switch between proliferation and differentiation of mesenchymal stem cells is critical for the development of normal tissues, and the prevention of tumors. How mesenchymal stem cells exit from the cell cycle and differentiate into alternative cell fates such as bone, fat, and muscle, is incompletely understood. We recently discovered that a WW domain-containing molecule, TAZ, functions as a transcriptional modulator to stimulate bone development while simultaneous blocking the… CONTINUE READING
58 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

Similar Papers

Loading similar papers…