TAS2R38 bitter taste genetics, dietary vitamin C, and both natural and synthetic dietary folic acid predict folate status, a key micronutrient in the pathoaetiology of adenomatous polyps.

@article{Lucock2011TAS2R38BT,
  title={TAS2R38 bitter taste genetics, dietary vitamin C, and both natural and synthetic dietary folic acid predict folate status, a key micronutrient in the pathoaetiology of adenomatous polyps.},
  author={Mark Lucock and Xiaowei Ng and Lyndell Boyd and Virginia M Skinner and Ron Wai and Sa Tang and Charlotte Chia Ch'i Naylor and Zo{\"e} Yates and Jeong-Hwa Choi and Paul D. Roach and Martin John Veysey},
  journal={Food & function},
  year={2011},
  volume={2 8},
  pages={
          457-65
        }
}
Taste perception may influence dietary preferences and nutrient intakes contributing to diet-related disease susceptibility. This study examined bitter taste genetics and whether variation in the TAS2R38 gene at three polymorphic loci (A49P, V262A and I296V) could alter dietary and systemic folate levels and dietary vitamin C intake, and whether a nutrigenetic circuit existed that might link bitter taste, folate/antioxidant status and risk for a colonic adenomatous polyp. TAS2R38 diplotype… CONTINUE READING
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