TANDEM: integrating automated allele binning into genetics and genomics workflows

  title={TANDEM: integrating automated allele binning into genetics and genomics workflows},
  author={Michael Matschiner and Walter Salzburger},
  volume={25 15},
SUMMARY Computer programs for the statistical analysis of microsatellite data use allele length variation to infer, e.g. population genetic parameters, to detect quantitative trait loci or selective sweeps. However, observed allele lengths are usually inaccurate and may deviate from the expected periodicity of repeats. The common practice of rounding to the nearest whole number frequently results in miscalls and underestimations of allelic richness. Manual sorting of allele lengths into… CONTINUE READING
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