TALE: a tale of genome editing.

  title={TALE: a tale of genome editing.},
  author={Mingjie Zhang and Feng Wang and Shifei Li and Yan Wang and Yun Bai and Xueqing Xu},
  journal={Progress in biophysics and molecular biology},
  volume={114 1},
Transcription activator-like effectors (TALEs), first identified in Xanthomonas bacteria, are naturally occurring or artificially designed proteins that modulate gene transcription. These proteins recognize and bind DNA sequences based on a variable numbers of tandem repeats. Each repeat is comprised of a set of ∼ 34 conserved amino acids; within this… CONTINUE READING