TACI regulates IgA production by APRIL in collaboration with HSPG.

@article{Sakurai2007TACIRI,
  title={TACI regulates IgA production by APRIL in collaboration with HSPG.},
  author={Daisuke Sakurai and Hidenori Hase and Yumiko Kanno and Hidefumi Kojima and Ko Okumura and Tetsuji Kobata},
  journal={Blood},
  year={2007},
  volume={109 7},
  pages={2961-7}
}
Transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) is a member of the tumor necrosis factor (TNF) receptor family that serves as a receptor for B-cell activating factor of the TNF family (BAFF) and as a proliferation-inducing ligand (APRIL). Although TACI is reported to function as a positive or negative regulator for B-cell responses, its roles remain elusive. Experiments using TACI siRNA into B cells indicated that TACI positively regulated APRIL-induced… CONTINUE READING

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