TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1.

@article{Ge2003TAB1betaG,
  title={TAB1beta (transforming growth factor-beta-activated protein kinase 1-binding protein 1beta ), a novel splicing variant of TAB1 that interacts with p38alpha but not TAK1.},
  author={Baoxue Ge and Xinsheng Xiong and Qing Jing and Jennifer L Mosley and Angela Filose and Dafang Bian and Shuang Huang and Jiahuai Han},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 4},
  pages={2286-93}
}
The mitogen-activated protein kinases (MAPKs) play an important role in a variety of biological processes. Activation of MAPKs is mediated by phosphorylation on specific regulatory tyrosine and threonine sites. We have recently found that activation of p38alpha MAPK can be carried out not only by its upstream MAPK kinases (MKKs) but also by p38alpha autophosphorylation. p38alpha autoactivation requires an interaction of p38alpha with TAB1 (transforming growth factor-beta-activated protein… CONTINUE READING
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