T4 Phage and Its Head Surface Proteins Do Not Stimulate Inflammatory Mediator Production

Abstract

Viruses are potent activators of the signal pathways leading to increased cytokine or ROS production. The effects exerted on the immune system are usually mediated by viral proteins. Complementary to the progress in phage therapy practice, advancement of knowledge about the influence of bacteriophages on mammalian immunity is necessary. Particularly, the… (More)
DOI: 10.1371/journal.pone.0071036

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