T4+ cell numbers are correlated with plasma glutamate and cystine levels: association of hyperglutamataemia with immunodeficiency in diseases with different aetiologies.

Abstract

Human immunodeficiency virus type 1 (HIV-1) seropositive individuals suffer from a depletion of T4+ T cells and have elevated plasma glutamate levels. Glutamate is also elevated in cancer patients, and several authors have shown that elevated extracellular glutamate levels inhibit competitively the membrane transport of cystine and cause a decrease of… (More)

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@article{Eck1992T4CN, title={T4+ cell numbers are correlated with plasma glutamate and cystine levels: association of hyperglutamataemia with immunodeficiency in diseases with different aetiologies.}, author={Hermann Eck and Thomas R Mertens and H Rosokat and Gerd F{\"a}tkenheuer and Craig S. Pohl and Matthias Schrappe and Volker Daniel and Helmut Naeher and Dr. M. Petzoldt and Prof. Dr. P. Drings}, journal={International immunology}, year={1992}, volume={4 1}, pages={7-13} }