T2Rs Function as Bitter Taste Receptors

@article{Chandrashekar2000T2RsFA,
  title={T2Rs Function as Bitter Taste Receptors},
  author={Jayaram Chandrashekar and Ken L. Mueller and Mark A Hoon and Elliot Adler and Luxin Feng and Wei Guo and Charles S. Zuker and Nicholas J. P. Ryba},
  journal={Cell},
  year={2000},
  volume={100},
  pages={703-711}
}
Bitter taste perception provides animals with critical protection against ingestion of poisonous compounds. In the accompanying paper, we report the characterization of a large family of putative mammalian taste receptors (T2Rs). Here we use a heterologous expression system to show that specific T2Rs function as bitter taste receptors. A mouse T2R (mT2R-5… CONTINUE READING