T20/DP178, an ectodomain peptide of human immunodeficiency virus type 1 gp41, is an activator of human phagocyte N-formyl peptide receptor.

Abstract

Human immunodeficiency virus type 1 (HIV-1) envelope protein gp41 mediates viral fusion with human host cells. The peptide segment T20/DP178, located in the C-terminus of the ectodomain of gp41, interacts with the N-terminal leucine zipper-like domain on gp41 to establish the fusogenic conformation of the virus. Synthetic T20/DP178 peptide is highly… (More)

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@article{Su1999T20DP178AE, title={T20/DP178, an ectodomain peptide of human immunodeficiency virus type 1 gp41, is an activator of human phagocyte N-formyl peptide receptor.}, author={Shu-hui Su and W. H. Gong and J. L. Gao and Weiming Shen and M C Grimm and X. Deng and Patricia Murphy and J. J. Oppenheim and J. M. Wang}, journal={Blood}, year={1999}, volume={93 11}, pages={3885-92} }