T1- and T2*-Mapping for Assessment of Tendon Tissue Biophysical Properties: A Phantom MRI Study.

@article{Bachmann2018T1AT,
  title={T1- and T2*-Mapping for Assessment of Tendon Tissue Biophysical Properties: A Phantom MRI Study.},
  author={Elias Bachmann and Andrea Bianca Rosskopf and Tobias G{\"o}tschi and Markus Klarh{\"o}fer and Xeni Deligianni and Monika Hilbe and Christian W. A. Pfirrmann and Jess Gerrit Snedeker and Michael A. Fischer},
  journal={Investigative radiology},
  year={2018},
  volume={54 4},
  pages={
          212-220
        }
}
OBJECTIVES The aim of this study was to quantitatively assess changes in collagen structure using MR T1- and T2*-mapping in a novel controlled ex vivo tendon model setup. MATERIALS AND METHODS Twenty-four cadaveric bovine flexor tendons underwent MRI at 3 T before and after chemical modifications, representing mechanical degeneration and augmentation. Collagen degradation (COL), augmenting collagen fiber cross-linking (CXL), and a control (phosphate-buffered saline [PBS]) were examined in… CONTINUE READING
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