T-type Ca2+ channels and alpha1E expression in spermatogenic cells, and their possible relevance to the sperm acrosome reaction.

@article{Livano1996TtypeCC,
  title={T-type Ca2+ channels and alpha1E expression in spermatogenic cells, and their possible relevance to the sperm acrosome reaction.},
  author={A Li{\'e}vano and Celia M. Santi and Carmen J. Serrano and Claudia Lydia Trevi{\~n}o and A R Bellv{\'e} and Arturo Hern{\'a}ndez-Cruz and Alberto Darszon},
  journal={FEBS letters},
  year={1996},
  volume={388 2-3},
  pages={150-4}
}
There is pharmacological evidence that Ca2+ channels play an essential role in triggering the mammalian sperm acrosome reaction, an exocytotic process required for sperm to fertilize the egg. Spermatozoa are small terminally differentiated cells that are difficult to study by conventional electrophysiological techniques. To identify the members of the voltage-dependent Ca2+ channel family possibly present in sperm, we have looked for the expression of the alpha 1A, alpha 1B, alpha 1C, alpha 1D… CONTINUE READING

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